BDBM50270039 (S)-1-((1S,2S)-1-cyano-2-phenylcyclopropylamino)-1-oxo-3-(thiophen-2-yl)propan-2-aminium 2,2,2-trifluoroacetate::CHEMBL478737

SMILES [NH3+][C@H](Cc1cccs1)C(=O)N[C@]1(C[C@H]1c1ccccc1)C#N

InChI Key InChIKey=FUYOZZGSCQXNCB-ZMSDIMECSA-O

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50270039   

TargetCathepsin G(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50270039((S)-1-((1S,2S)-1-cyano-2-phenylcyclopropylamino)-1...)
Affinity DataIC50: >5.00E+4nMAssay Description:Blockade of cathepsin G processing in human U937 cells by densitometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin G(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50270039((S)-1-((1S,2S)-1-cyano-2-phenylcyclopropylamino)-1...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of cathepsin G activation in beta-estradiol differentiated mouse EcoM-G cells after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed